Avantes has extensive experience in the biomedical industry. Over the years, they have supported the development of both non-invasive and invasive spectrometry solutions for tissue and blood parameter measurements.

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Some of the important medical indicators which Avantes has worked with include oxygen, hemoglobin, cytochrome and water concentration measurements in tissues and in the venous system. The AvaSpec-ULS2048-USB2 and the SensLine instruments are frequently recommended for these applications, coupled together with AvaLight-HAL tungsten halogen light source providing excellent, high-stability VIS/NIR light for biomedical applications involving reflection measurements. Avantes worked successfully with many customers to enable continuous measurements of oxygen saturation, concentration of total, oxygenated and de-oxygenated hemoglobin.

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Some examples of implementations of Avantes solutions:

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• Angiology/Pharmacology - Monitoring of the oxygen saturation after the application of vaso-active substances. Oxygen changes caused by Reynaud syndrome and microcirculation diseases in tissue.

• Dermatology - Detection of local - regional perfusion diseases, recurrence of melanomas.

• Diabetology - Micro-angiopathy, early detection of Endotheld dysfunction and ulceration.

• Cardio surgery - Oxygen consumption of the heart muscle during and after bypass operations.

• Neurosurgery/Oncology - Quantifying of oxygen consumption of (brain) tumours before/after radiation or operations.

• Pediatry/Gynecology - monitoring of oxygen concentration of critically ill newborns during birth.

• Plastic surgery/Transplantation medicine - Monitoring of transplanted and re-implanted tissues, bones or organs

• Accident surgery - Characterisation of burned or frozen skin tissues.

• European project: Cancer diagnosis with miniature spectrometers - Watch the video here